abstract |
The present invention relates to 2-amino-4-arylpyrimidine and 2-amino-4-aryltriazine compounds as inhibitors of the heat shock protein 90 family of chaperone proteins. The invention also features pharmaceutical compositions and kits containing the compounds and compositions of the invention. The invention further relates to the medical use of these compounds and compositions for the treatment of a disease in a subject. For example, the disease is a neurodegenerative disease. [Selection] Figure 1 |