| abstract |
General formula (I) (wherein one of X 1 and X 2 represents N and the other of X 1 and X 2 represents —C (CH 3 ), and A represents an unsubstituted or substituted 5 , 6 or 10 membered aryl or heteroaryl, n is 0 or 1, and B is a bicyclic hetero moiety as defined herein. The compounds are phosphodiesterase 10A inhibitors and may find use in medicine in the treatment of diseases and disorders of psychotic, neurological and cognitive function. (I) |