http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017517579-A
Outgoing Links
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|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
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| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-14 |
| filingDate | 2015-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017517579-A |
| titleOfInvention | Method for treating non-small cell lung cancer and / or small cell lung cancer using thienotriazolodiazepine compound |
| abstract | In a mammal comprising administering to a patient a pharmaceutically acceptable amount of a thienotriazolodiazepine compound of formula (1) or a pharmaceutically acceptable salt thereof or a hydrate or solvate thereof. Method for treating non-small cell lung cancer and / or small cell lung cancer: [Wherein, R 1 represents alkyl having 1 to 4 carbon atoms, and R 2 represents a hydrogen atom; a halogen atom; or 1 to 4 carbon atoms which may be substituted with a halogen atom or a hydroxyl group. R 3 is a halogen atom; a halogen atom, an alkyl having 1 to 4 carbon atoms, an alkoxy having 1 to 4 carbon atoms, or phenyl optionally substituted with cyano; —NR 5 — ( CH 2 ) m —R 6 (wherein R 5 is a hydrogen atom or alkyl having 1 to 4 carbon atoms, m is an integer of 0 to 4, and R 6 is substituted with a halogen atom) Or —NR 7 —CO— (CH 2 ) n —R 8 (wherein R 7 is a hydrogen atom or alkyl having 1 to 4 carbon atoms, n is an integer of 0 to 2, R 8 A phenyl or pyridyl optionally substituted by halogen atom), and, R 4 is -. (CH 2) in a -CO-NH-R 9 (wherein, a is an integer of from 1 to 4 R 9 is alkyl having 1 to 4 carbon atoms; hydroxyalkyl having 1 to 4 carbon atoms; alkoxy having 1 to 4 carbon atoms; or alkyl having 1 to 4 carbon atoms; 4 is an alkoxy having 4 carbon atoms, phenyl or pyridyl which may be substituted with an amino or hydroxyl group.) Or — (CH 2 ) b —COOR 10 (wherein b is an integer of 1 to 4) , R 10 is alkyl having 1 to 4 carbon atoms. ]. [Selection] Figure 1A |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7311498-B2 |
| priorityDate | 2014-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 262.