http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017516845-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D413-14 |
| filingDate | 2015-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017516845-A |
| titleOfInvention | Hydrazide compounds as blood coagulation factor Xa inhibitors |
| abstract | The present invention relates to a novel compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein X is selected from a 3-9 membered carbon ring or a benzo ring thereof, a 4-10 membered heterocyclic ring or a benzo ring thereof. Y and Z are each independently selected from 4-9 membered saturated heterocycles, and R 1-3 are each independently from H, F, Cl, Br, I, CN, OH, SH, NH 2 , CHO, COOH. is selected, or an optionally substituted C 1-10 alkyl group or a heteroalkyl group substituted with R 01, C 3-10 cycloalkyl group or a heterocycloalkyl group, a C 3-10 cycloalkyl group or a heterocycloalkyl group Selected from C 1-10 alkyl groups or heteroalkyl groups. The compounds of the present invention can be used as anticoagulants for treating and preventing thrombosis. The present invention meets the real need for selectivity and potent inhibitors of blood clotting factor Xa by providing potent inhibitors of blood clotting factor Xa. [Chemical 1] |
| priorityDate | 2014-05-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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