http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017514525-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-20 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-902 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-22 |
| filingDate | 2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017514525-A |
| titleOfInvention | TAL effector nuclease for targeted knockout of HIV co-receptor CCR5 |
| abstract | With respect to a novel TAL effector nuclease (TALEN) for targeted knockout of HIV co-receptor CCR5, in one aspect, a TAL effector nuclease pair comprising first and second TAL effector nuclease monomers, wherein each TAL effector nuclease monomer comprises: An endonuclease domain having type II endonuclease activity and a TAL effector DNA binding domain having a plurality of repeating units each having a variable amino acid pair RVD, and a) a TAL effector DNA of a first TAL effector nuclease monomer The binding domain binds to the target sequence GCTGGTCATCCCTCATCCTG (SEQ ID NO: 1) and / or the RVD sequence NH HD NG NH NH NG HD NI N B) the TAL effector DNA binding domain of the second TAL effector nuclease monomer binds to the target sequence AGATGTCAGTCATGCTCTT (SEQ ID NO: 2) and / or the RVD sequence NI NN NI, including HD HD NG HD NI NG HD HD NG NN A TAL effector nuclease pair comprising NG NN NG HD NI NH NG HD NI NG NH NH NG HD NG NG is provided. [Selection] Figure 1 |
| priorityDate | 2014-05-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.