http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017513865-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-763 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-093 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 |
| filingDate | 2015-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017513865-A |
| titleOfInvention | Peptides derived from RS1 that down-regulate glucose inhalation and increase insulin sensitivity after a glucose-rich diet |
| abstract | The invention includes QEP or a QEP derivative thereof for use in the prevention or treatment of a disease or disorder caused by physiologically linked or associated glucose and / or galactose intake It relates to a pharmaceutical composition to be administered under high sugar conditions, comprising a (poly) peptide comprising it, a nucleic acid molecule encoding said (poly) peptide, or a vector comprising said nucleic acid molecule. Furthermore, the pharmaceutical composition of the present invention is for use to increase insulin sensitivity. The present invention further relates to a food composition comprising the (poly) peptide. The invention also relates to a method for screening and / or identifying suitable compounds for preventing or treating said disease or disorder under high sugar conditions. The present invention may further inhibit (SGLT1-mediated) glucose and / or galactose uptake into cells expressing ODC and / or inhibition of inhibitors of glucose and / or galactose uptake into cells expressing ODC. It relates to a method for screening and / or identifying compounds that modulate ornithine decarboxylase (ODC) that can enhance the effect. The invention further provides a method for predicting patient non-response or response to said (poly) peptide, a method for stratifying patients for prevention or treatment with said (poly) peptide, and said disease or disorder Relates to a kit for determining whether a patient suffering from is non-responder or responder to said polypeptide. The invention further relates to a method for developing and / or planning suitable compounds / drugs for preventing or treating said diseases or disorders. |
| priorityDate | 2014-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 741.