| abstract |
Disclosed are compositions and methods relating to or derived from anti-WISP1 antibodies. More specifically, fully human antibodies that bind to WISP1, WISP1-binding fragments and derivatives of such antibodies, and WISP1-binding polypeptides comprising these fragments are disclosed. Furthermore, nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells containing such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and such Disclosed are methods of using antibodies, antibody fragments and derivatives and polypeptides, eg, methods of treating or diagnosing a subject having a disorder or condition associated with WISP1. Also disclosed are methods for treating or preventing various cancer or inflammatory diseases and various diseases of the heart, bone / joint or lung. |