abstract |
The present invention relates to a method for improving the solubility of a physiologically active protein or peptide compared to a physiologically active protein or peptide to which no immunoglobulin Fc fragment is bound, comprising the step of binding the physiologically active protein or peptide to an immunoglobulin Fc fragment, And a composition for improving the solubility of a physiologically active protein or peptide, comprising an improved solubility compared to a composition containing no immunoglobulin Fc fragment. |