| abstract |
The present invention relates to ligand-cytotoxic drug conjugates, methods for their production and pharmaceutical use. More specifically, the present invention relates to ligand-cytotoxicity in the manufacture of drugs for the treatment of cancer by ligand modulation, ligand-cytotoxic drug conjugates of the general formula Pc- (XYD) n , methods for their preparation and receptor modulation The use of drug conjugates and pharmaceutical compositions comprising them is provided. [Selection figure] None |