http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017507963-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 |
filingDate | 2015-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2017507963-A |
titleOfInvention | A combination comprising a BTK inhibitor and an AKT inhibitor |
abstract | BTK inhibitors such as 1-[(3R) -3- [4-amino-3- (4-phenoxyphenyl) -1H-pyrazolo [3,4-d] pyrimidin-1-yl] piperidin-1-yl ] Prop-2-en-1-one or a pharmaceutically acceptable salt thereof, and an AKT inhibitor compound such as N-{(1S) -2-amino-1-[(3-fluorophenyl) methyl] ethyl } -5-chloro-4- (4-chloro-1-methyl-1H-pyrazol-5-yl) -2-thiophenecarboxamide or a pharmaceutically acceptable salt thereof, and any additional antineoplastic agents. A novel combination comprising; a pharmaceutical composition comprising the combination and a method of using the combination and composition for the treatment of conditions where BTK inhibition and / or AKT inhibition is beneficial, eg, cancer. |
priorityDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 690.