| abstract |
The present invention in the field of immunology and infectious diseases relates to opsonizing and protective antibodies specific for Gram positive bacteria, in particular for carbohydrate structures exposed on the surface of the bacteria. The invention includes monoclonal and chimeric antibodies and fragments, regions and derivatives of the antibodies. The present invention also relates to the epitope to which the antibody of the present invention binds and the sequence, fragment and region of the epitope. Both the antibodies and peptides containing the epitopes, and regions and fragments thereof, can be used for diagnostic, prophylactic and therapeutic applications. [Selection] Figure 1 |