| abstract |
A novel extract from green coffee beans containing polyphenols and biologically active compounds, e.g. chlorogenic acid, in significantly higher concentrations (70-80%) than in extracts of prior art methods (40-50%) Is disclosed. The extract is more capable of suppressing oxidative stress and destroying free radicals and provides health benefits due to its anti-obesity, anti-diabetes, anti-hypertension, anti-tumor, and antacid properties. By using a polar solvent having a polarity less than that of the alcohol used for extraction, ie methanol or ethanol, higher concentrations of bioactive compounds were realized. By using such a less polar solvent, such as n-butyl alcohol, ethyl acetate, or acetone, the enriched chlorogenic acid fraction is extracted into the extract while leaving polar impurities in the aqueous medium. The The resulting extract has a significantly higher content of polyphenols and chlorogenic acid in the range of 70-80% and has the characteristic HPLC profile shown in FIG. |