| abstract |
Provided are compounds of formula I or stereoisomers, tautomers or pharmaceutically acceptable salts thereof useful in the treatment of disease. Use of a compound of formula I or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such diseases or related pathological conditions A method is disclosed. The invention relates to compounds that are useful for treating hyperproliferative and neoplastic diseases by inhibiting serine / threonine kinases and inhibiting signal transduction pathways that are generally over-activated or over-expressed in cancer tissues. |