http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017501214-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-00 |
filingDate | 2014-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2017501214-A |
titleOfInvention | DOTAM derivatives for therapeutic use |
abstract | DOTAM DERIVATIVES FOR THERAPEUTIC USE The present invention relates to compounds of formula I that are either stereoisomers or mixtures of stereoisomers in any proportion, and pharmaceutically acceptable salts thereof. Where M is absent or present, Gd, Yb, Mn, Cr, Cu, Fe, Pr, Nd, Sm, Tb, Yb, Dy, Ho, Er, Eu, Ga, 68Ga, 64Cu, 99mTc 177Lu, 67Ga, 111In, 99Mo, positively charged metal ions, and A1, A2, A3, and A4, L1, L2, L3, and L4, Y1, Y2, Y3, and Y4, Z1, Z2, Z3 and Z4 have the meaning indicated in the claims. The compounds of formula I are valuable pharmacologically active compounds and are suitable for the treatment of osteoarthritis. The present invention further relates to methods for the preparation of compounds of formula I, medicaments containing them and their use as pharmaceutical compositions. [Selection figure] [Chemical formula 1] |
priorityDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 555.