abstract |
We have the sequence CXXXRCXXXHSRVPFP (SEQ ID NO: 1) (wherein X represents an amino acid residue), for example, a sequence selected from the group consisting of SEQ ID NO: 2 to SEQ ID NO: 18, preferably CLQRCMPLHSRVPFP (sequence An ELABELA polypeptide comprising number 2), or a fragment, homologue, variant or derivative thereof, is described, the polypeptide being capable of maintaining stem cell self-renewal and / or pluripotency. |