| abstract |
The present invention is linked to a position corresponding to position 35 of hPYY (1-36), a PYY compound having an amino acid substituted with β-homoarginine, and a position corresponding to position 7 of hPYY (1-36). And their derivatives having modified groups. The compounds of the present invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, as well as medical uses of PYY compounds. |