| abstract |
[PROBLEMS] To provide a preparation which reduces symptoms such as skin discomfort, skin irritation, skin exfoliation, erythema or pruritus, which are side effects appearing during application of adapalene aqueous gel to the affected area of the face. SOLUTION: 0.1% by mass of adapalene is blended with 1 to 3% by mass of squalane, 0.1 to 0.5% by mass of glyceryl monostearate, and 0.5 to 6.5% by mass of petrolatum. %, 0.2-0.4% by mass of carboxyvinyl polymer, and 38-42% by mass of concentrated glycerin, and adjusting the pH to 6.0-7.5, or adapalene 4 to 8% by mass of squalane in 0.1% by mass, 0.5 to 1.0% by mass of glyceryl monostearate, 0.2 to 0.4% by mass of carboxyvinyl polymer, and concentrated glycerin 45 The lotion which mixes -55 mass% and adjusts pH to 6.0-7.5. [Selection figure] None |