| abstract |
An inhalable pharmaceutical composition is provided. An inhalable pharmaceutical composition comprising a dispersion of liposome particles suitable for continuous aerosolization, comprising a dispersion of liposome particles having an average diameter of about 30-500 nm, each liposome particle being hydrophobic Wherein the ratio of hydrophobic bioactive substance: phospholipid is between about 5: 1 and about 1: 5, wherein the hydrophobic bioactive substance is selected from the group consisting of the bioactive substance, phospholipid, and aqueous dispersion medium. About 0.1-30% w / w of the composition, phospholipid is about 0.1-30% w / w of the composition, and the liposome particles are dispersed in an aqueous dispersion medium, where the test When administered to the body, the composition is characterized by continuous aerosolization sufficient to provide a subject with a therapeutic dose of a hydrophobic bioactive substance. [Selection figure] None |