http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017203022-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1d29f7ac2c7f9be9f7dae1a83bbb5c92 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
filingDate | 2016-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26238b5b136e0aa4cb0a3870f2415fc7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96c3bb384b2f1520a688ea916e143a9b |
publicationDate | 2017-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2017203022-A |
titleOfInvention | Manufacturing method of ezetimibe |
abstract | PROBLEM TO BE SOLVED: To reduce the number of ring-opened compounds efficiently and to have high purity (3R, 4S) -1- (4-fluorophenyl)-[3 (S) -hydroxy-3- (4-fluorophenyl) ) Propyl]-(4-hydroxyphenyl) -2-azetidinone. (3R, 4S) -1- (4-fluorophenyl)-[3 (S) -hydroxy-3- (4-fluorophenyl) propyl]-from a mixed solvent containing alcohol, water, and acid. By crystallizing (4-hydroxyphenyl) -2-azetidinone, high purity (3R, 4S) -1- (4-fluorophenyl)-[3 (S ) -Hydroxy-3- (4-fluorophenyl) propyl]-(4-hydroxyphenyl) -2-azetidinone crystals. [Selection figure] None |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115453004-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115453004-B |
priorityDate | 2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.