| abstract |
PROBLEM TO BE SOLVED: To provide innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of histidyl tRNA synthetase. A novel identified protein fragment of an aminoacyl-tRNA synthetase, a composition comprising the polynucleotide encoding it and its complement, related drugs, and its use in diagnostic, drug discovery, research and therapeutic applications. Law is provided. Embodiments of the present invention generally relate to the discovery of protein fragments of aminoacyl-tRNA synthetase (AARS) that have non-canonical biological activity such as extracellular signaling activity and / or other features related to therapy and diagnosis. . [Selection] Figure 1A |