http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017195862-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cbd7eb2e3a76b55013b3156a0375ecd5 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-554 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5513 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 |
| filingDate | 2016-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c439839c2c15e5f4aa53dee9bd11ee4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbd4f063dfe16f8ee619d360c00813ac |
| publicationDate | 2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017195862-A |
| titleOfInvention | Method for determining blood drug concentration increase risk and drug dose determination method of clozapine or its derivatives |
| abstract | An object of the present invention is to develop a method for determining the risk of an increase in blood concentration of clozapine or a derivative thereof and to provide a method for determining a drug dose for determining an optimal dose. In the present invention, i) the 421st base of the ABCG2 gene derived from a subject is detected, and ii-a) when the genotype of the detected base is C / A or A / A, A method for determining the risk of an increase in blood drug concentration, comprising determining that there is a risk of increasing the blood concentration of the drug when one or more drugs selected from the group consisting of clozapine, olanzapine and quetiapine are administered to the subject And ii-b) when the genotype of the detected base is C / A or A / A, one or more drugs selected from the group consisting of clozapine, olanzapine and quetiapine are given to the subject Provided is a method for determining drug dosage, comprising determining that the dosage of a drug should be reduced when administered. [Selection figure] None |
| priorityDate | 2016-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 55.