| abstract |
The present invention provides a complex of cytomegalovirus proteins. The present disclosure provides an isolated human cytomegalovirus (HCMV) membrane protein complex comprising gH, gL and at least another HCMV glycoprotein. In some embodiments, the complex consists of gH, gL, and gO. In other embodiments, the complex consists of gH, gL, pUL128, pUL130, and pUL131A. The present disclosure also provides a process for expressing and purifying the complex, as well as the use of the complex in subsequent immunogenic compositions and vaccines. [Selection figure] None |