abstract |
An immunoglobulin single variable domain (ISV), protein or polypeptide for use in the treatment of a disease in humans. An immunoglobulin single variable domain (ISV) that is a Nanobody, or that contains a VH sequence (ie, other than a Nanobody) or is derived from a VH sequence, the sequence VTVSS (X) n An immunoglobulin single variable domain (ISV) having the C-terminus of: or a protein or polypeptide containing such an ISV (preferably such a Nanobody) at its C-terminus. [Selection figure] None |