http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017149787-A

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f24203d528af5341df753a4f79f76f4e
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-61
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
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filingDate 2017-06-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_566d8c89cf078cb5e82e788432ae7a98
publicationDate 2017-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-2017149787-A
titleOfInvention Cationic polysaccharide copolymer delivery system
abstract [Purpose] Uses cationic derivatives of polysaccharides to polymerize olefinic compounds in water to prepare latex solutions of non-surfactants, form supramolecular complexes with drugs, and deliver drugs to cells Get delivery material. [Structure] A latex solution comprising a polymer obtained by polymerizing a cationic derivative of a polysaccharide with an olefin compound in water. A complex obtained by reacting various drugs with this. [Effect] When such a drug delivery material is used, a drug having a side effect can be used safely and stably. In order to enhance the effect of the drug, selective permeation of the cell membrane and intracellular substrate selectivity are important. Furthermore, in order to increase the selective permeability of the cell membrane and for its supramolecularity, it is necessary to have a hydrophobic hydrophilic domain. Specifically, latex composed of a copolymer material of a cationic polysaccharide and a vinyl monomer is used. To form a complex with the drug. Its supramolecularity is an important factor for selective permeation of cell membranes and substrate selectivity in cells. It was found that such drug delivery materials are very promising industrially because they are stable and expected to be used for coating. [Selection figure] None
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114957810-A
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priorityDate 2012-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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