| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_431309bc8dab94a0ee0e2aa5aeacd48d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_537aedd607603b452a2b475a3d3afe1f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6031
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-6056 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6811
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6815
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-21
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-37 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
| filingDate |
2017-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4849f9dcf5882b464d30c3ca72cc85fc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95bc612f8b24fee635ff067094ac1296
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9a43e2a9e20d8feb96e8d052efe2bcb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_891cc700f10e0ab25a2c0b922e14bda4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7f8f35d0040fcbb2e741da278ceae44 |
| publicationDate |
2017-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-2017149784-A |
| titleOfInvention |
Method for reducing immunogenicity against factor VIII in an individual undergoing factor VIII therapy |
| abstract |
A method for reducing immunogenicity against factor VIII in an individual receiving factor VIII therapy. The present disclosure provides for a chimeric hybrid comprising FVIII and Fc against a subject at risk of developing an inhibitory FVIII immune response (including anti-FVIII antibodies and / or cell-mediated immunity). Methods of administering a Factor VIII (FVIII) polypeptide are provided. This administration is sufficient to promote clotting and induce immune tolerance to FVIII. The chimeric polypeptide may comprise full length FVIII, or FVIII polypeptide comprising a deletion (eg, complete or partial deletion of the B domain). [Selection] Figure 1 |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11286528-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2019077690-A |
| priorityDate |
2012-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |