| abstract |
Kind Code: A1 The present invention provides a good immune response in elderly patients and does not have the problems of the prior art, or is at least reduced to a considerable extent, and further allows induction of a Th1 immune response, preferably after administration Th1 immunity Providing a vaccine that does not cause a shift from a response to a Th2 immune response and does not have problems such as integration of DNA into the genome, gene disruption, and formation of anti-DNA antibodies that can occur with a DNA-derived vaccine. Aged comprising a complex of at least one mRNA encoding at least one antigen and a polymer carrier formed by a specific oligopeptide or a disulfide-bridged cationic component comprising the specific oligopeptide as a repeat unit Patient vaccine. [Selection figure] None |