Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_87a863132c68cf0f62015bbd5d05ab38 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B50-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B40-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
filingDate |
2017-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c9f379511c2624f4057a2fba19ecf18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01eae4bc3c5aa5bd9befc7eea2af36c8 |
publicationDate |
2017-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-2017121238-A |
titleOfInvention |
Fibronectin type III repeat-based protein scaffold with a selective binding surface |
abstract |
Protein scaffolds and scaffold libraries based on fibronectin type III (FN3) repeats with selective binding surface design are provided. A method for making a library of fibronectin type III module (FN3) domains having a diversified C-CD-F-FG selective surface formed by Cβ strands, CD loops, Fβ strands, and FG loops. A. Providing a reference FN3 domain polypeptide having an amino acid sequence that is at least 80% identical to an amino acid sequence comprising a particular sequence; b. The reference FN3 is mutated by mutating at least one Cβ strand residue and at least one Fβ strand residue to form the FN3 domain library having the diversified C-CD-F-FG selective surface. Introducing diversity into the domain polypeptide. [Selection figure] None |
priorityDate |
2011-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |