| abstract |
Compositions and methods for antigen-binding proteins that bind to human thymic stromal lymphocytic neoplastic factor (TSLP), including antibodies. SOLUTION: a. : I. A light chain CDR3 sequence that differs by no more than 2 amino acid additions, substitutions, and / or deletions from a CDR3 sequence selected from the group consisting of the light chain CDR3 sequences of A1-A27; ii. A light chain CDR3 sequence selected from the specific sequence group, and b. : I. A heavy chain CDR3 sequence that differs by no more than 3 amino acid additions, substitutions, and / or deletions from a CDR3 sequence selected from the group consisting of the heavy chain CDR3 sequences of A1-A27; ii. An isolated antigen binding protein comprising an amino acid sequence selected from the group consisting of a heavy chain CDR3 sequence selected from the group consisting of a specific sequence, and the antigen binding protein specifically binds to TSLP An antigen binding protein. [Selection figure] None |