| abstract |
An improved formulation of amphoteric liposomes containing neutral lipids. Amphoteric liposomes containing neutral lipids, wherein the neutral lipids are selected from the group consisting of cholesterol or a mixture of cholesterol and at least one neutral or zwitterionic lipid, Amphoteric liposomes with a (neutral) of 0.3 or less. Preferably, the kappa (neutral) of the mixture of cholesterol and at least one neutral or zwitterionic lipid is less than 0.25, preferably less than 0.2, most preferably less than 0.15. [Selection figure] None |