abstract |
Disclosed is a pharmaceutical composition comprising a novel pyrrolidine compound having melanocortin receptor agonist activity or a pharmacologically acceptable salt thereof as an active ingredient. A pyrrolidine derivative represented by the formula [I] or a pharmacologically acceptable salt thereof. [Ring A is a substituted / unsubstituted aryl group, etc .; R 1 is a substituted / unsubstituted alkyl group, etc .; R 2 is a halogen atom, etc .; R 3 is an alkyl group substituted with a substituted / unsubstituted aryl group, etc .; R 4 is H or an alkyl group, or R 3 and R 4 are bonded to each other at the end, and may partially contain a double bond, which is a substituted / unsubstituted nitrogen-containing aliphatic heterocyclic ring. [Selection figure] None |