abstract |
A new type of mesenchymal stem cell (MSC), an osteogenic cell having a similar phenotype, co-expressing at least one mesenchymal marker, preferably at least CD105 and CD34, said cell and cell Providing additional products, including populations, and methods for their use in bone therapy. MSC cells isolated from bone marrow coexpressing at least CD105 and CD34, or MSC cells isolated from bone marrow coexpressing CD105, CD90, CD73 and CD34 are increased and osteogenic differentiation in vitro MSC cells isolated from bone marrow, together with fibroblast growth factor 2 (FGF-2), granulocyte monocyte CSF (GM-CSF), interferon (IFN) -gamma, platelet-derived growth Exposure to one or more factors selected from Factor (PDGF), FGF-1, and FGF-3. [Selection figure] None |