| abstract |
There is a need for new safe and effective treatments for pain by targeting small molecule mediators or exacerbators of pain, such as NGF. The above problems have been solved by providing an antibody that interacts with or binds to the human nerve growth system (NGF), thereby neutralizing the function of NGF. The present invention also provides for the neutralization of NGF function by administering pharmaceutical compositions of such antibodies, and pharmaceutically effective amounts of anti-NGF antibodies, and particularly for NGF-related disorders (eg, chronic pain). Provide a method for treating Also provided is a method of determining the amount of NGF in a sample using an anti-NGF antibody. [Selection figure] None |