abstract |
A novel family of cell surface serpentine transmembrane antigens is provided. A STRAP-1 protein, which is a prototype member of the tortuous transmembrane antigen (STRAP) family expressed in the prostate and having a specific sequence, is structurally composed of six transmembrane domains and intracellular A 339 amino acid protein characterized by a molecular topology having N- and C-termini, an isolated polynucleotide encoding said protein, a recombinant vector comprising said polynucleotide and a host cell comprising said expression vector. [Selection] Figure 1A-1 |