http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017079597-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_80787665b837ed3eb503bbcd27c0043a |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J20-26 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-0781 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J20-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-00 |
filingDate | 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50a139d03d14cec6799c5efb445d104e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d48fc6df026742ac8abd33ba56e44de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4481f49dd1e3ef48704183febfcd9ba0 |
publicationDate | 2017-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-2017079597-A |
titleOfInvention | Cell separation device and cell separation method |
abstract | The present invention provides a cell separation apparatus and a cell separation method capable of selecting cells having high antibody-producing ability from a group of candidate cells with a simple process with little damage. A cell separation apparatus includes an operation unit in which an incubator having a plurality of wells is installed, a seeding unit for seeding candidate cells in a culture solution, and a temperature control unit for adjusting the temperature of the culture solution. The reagent adding means 106 for adding the anti-membrane protein antibody to the culture solution and the recovery means 104 for collecting the culture solution are provided. On the inner wall surface of the well, a protein binding site having antibody binding ability and a temperature responsive site in which the three-dimensional structure changes due to temperature change, the anti-membrane protein antibody is added to the cultured candidate cells, The medium is changed from the culture temperature of the candidate cell to a temperature exceeding the phase transition temperature of the temperature-responsive site, leaving non-antibody-producing cells bound to the protein binding site via anti-membrane protein antibodies, and antibody-producing cells Only collect and recover. [Selection] Figure 1 |
priorityDate | 2015-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 66.