http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017078081-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7adb29875a27e033270185d9de2669ab |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-044 |
| filingDate | 2016-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7021a5c410201331a92f78fc59bf0c0b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1a0bc2008217bcd775bfb6292f497a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0cb5290a0eef1f8af7b3490dd79448b |
| publicationDate | 2017-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017078081-A |
| titleOfInvention | Tetracyclic anthraquinone derivatives |
| abstract | A tetracyclic anthraquinone antibiotic such as doxorubicin or daunorubicin, which has limited clinical application due to side effects such as bone marrow suppression and cardiotoxicity, while maintaining good anticancer and / or antitumor activity at the cellular level, Provided is a tetracyclic anthraquinone derivative that has water solubility, stability, and good tolerance in an animal body and is clinically applicable. A polyoxyalkylene group having a number of added moles of 11 or less, a morpholino group, a piperazino group, a purine residue, etc. is substituted for the 14-position hydroxyl group of 3′-pyrrole adriamycin via a dicarboxylic acid residue such as succinic acid. Tetracyclic anthraquinone antibiotics, to which an amino group having a modified hydrocarbon group is bonded. [Selection figure] None |
| priorityDate | 2012-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 441.