http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017075129-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c5f081d104cf9efd8cfc5e3035f44fc1 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 |
| filingDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c14bc395bb2bb92b50b3a4454af4e404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b6f363b5375fa07cfc4e12b2cc149cc |
| publicationDate | 2017-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017075129-A |
| titleOfInvention | TRPV1 activity inhibitor |
| abstract | An object of the present invention is to provide a test substance evaluation method for evaluating whether or not a test substance is a substance having an action of amplifying the TRPV1 activity suppression action by menthol with a simple operation and high reproducibility. TRPV1-expressing cells are contacted with a test sample containing a TRPV1 agonist, a test substance and menthol and a comparative sample containing a TRPV1 agonist and menthol, respectively, and cells of TRPV1-expressing cells before and after contact with the test sample A change in the intracellular calcium concentration and a change in the intracellular calcium concentration of the TRPV1-expressing cells before and after contact with the comparative sample, and a change in the intracellular calcium concentration in the TRPV1-expressing cells before and after contact with the test sample and the comparative sample The test substance evaluation method which evaluates whether the said test substance is a substance which has the effect | action which amplifies the TRPV1 activity suppression effect by a menthol based on the change of the intracellular calcium concentration of the TRPV1 expression cell before and behind contact. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017074024-A |
| priorityDate | 2015-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.