| abstract |
PROBLEM TO BE SOLVED: To provide an improved system, apparatus and method for caring for and evaluating a perfusion state useful for effective preservation of a heart ex vivo. The unique properties of cardiomyocytes that produce / generate lactate when oxygen is deficient and metabolize / utilize lactate for energy generation when fully perfused with oxygen, 1 In order to evaluate the total perfusion status of the isolated heart, 2) the metabolic status of the isolated heart, and 3) the total vessel patency of the isolated donor heart, the arterial blood lines and veins of the organ care system cardiac perfusion device A system, apparatus, and method for measuring and comparing lactate values in blood lines to indicate proper perfusion and oxygenation close to physiological conditions for cardiomyocytes. [Selection figure] None |