| abstract |
An APJ receptor agonist is provided that can be used to treat various cardiovascular and other conditions. (2S, 3R) -N- (4- (2,6-dimethoxyphenyl) -5- (2-methoxy-4-pyridinyl) -4H-1,2,4-triazol-3-yl) -3- (5-methyl-2-pyrimidinyl) -2-butanesulfonamide, (2S, 3R) -N- (4- (2,6-dimethoxyphenyl) -5- (2-methyl-4-pyridinyl) -4H-1,2,4-triazol-3-yl) -3- (5-methyl-2-pyrimidinyl) -2-butanesulfonamide and the like, 1,2,4-triazole with a pyridine ring, pyrimidine, etc. A compound substituted with a substituent. [Selection figure] None |