| abstract |
Novel compounds in the regulation of Janus kinase (JAK) pathway, inhibition of one or more JAK kinases, and regulation of JAK pathway or treatment of conditions where inhibition of JAK kinase, particularly JAK3, is therapeutically useful Providing methods for their use. A compound represented by the formula IA or a salt thereof. A pharmaceutical composition comprising the compound or a salt thereof. Administering the composition to administer a pharmaceutical composition to treat a T cell mediated autoimmune disease. A method of treating allograft rejection in transplant recipients in allogeneic transplants such as sputum, kidney, heart, liver or lung transplants. (R is independently H, substituted / unsubstituted C1-6 alkyl, C (O) -C1-6 alkyl, CO2-C1-6 alkyl, etc.) [Selection] None |