abstract |
Provided is an IgG Fc variant with improved affinity for Fc receptor FcRn. A polypeptide comprising an Fc variant of an IgG Fc polypeptide comprising a change of Fc from position 434 to serine and position 311 to isoleucine or valine, said numbering being the EU of Kabat et al. Polypeptide by index. [Selection] Figure 1a |