http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2017051185-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f9af914ed2fb00cd4f1b8b1a28964e4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-16 |
| filingDate | 2016-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b8d24337f1fb3a0158185eadfd41aaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d975a010f5ffb20e8863f36de949610 |
| publicationDate | 2017-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-2017051185-A |
| titleOfInvention | Genetically modified Clostridium saccharoper butylacetonicum species microorganisms whose genome sequence has been specifically converted, methods for producing the same, and uses thereof |
| abstract | [PROBLEMS] By eliminating the function of by-products such as acetic acid and butyric acid of Clostridium saccharoperbutylacetonicum microorganisms without depending on the insertion of foreign genes, the safety is improved and the equipment costs are reduced. To provide a novel high-butanol-producing bacterium that can be expected to reduce waste disposal costs and a method for producing the same. A Clostridium saccharoperperbutylacetonicum species microorganism lacking the function of a butyrate-synthesizing enzyme gene involved in the pathway of butyric acid produced from butyryl-CoA, which contains insertions and / or deletions in the gene Microorganisms characterized by not having. DNA encoding a chimeric RNA composed of crRNA and tracrRNA containing a sequence complementary to the target strand of the target nucleotide sequence in the butyrate gene, and a mutant Cas protein and deaminase in which at least one of the DNA strands is cleaved By introducing a DNA encoding a fusion protein with a microorganism that can be replicated in a Clostridium saccharoperbutylacetonicum microorganism to replace a specific base in the target nucleotide sequence, A method for producing the above-mentioned butyric acid synthase gene-deficient microorganism, wherein the enzyme gene function is thereby deleted. A method for producing butanol by culturing the butyric acid synthase gene-deficient microorganism. [Selection figure] None |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10150974-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-7126403-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2020022378-A |
| priorityDate | 2015-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 689.