abstract |
Complete humans that recognize IL-17F, IL-17F homodimer, IL-17A, IL-17A homodimer, and / or heterodimer IL-17A / IL-17F protein complex Providing monoclonal antibodies. Further provided are methods of using monoclonal antibodies as therapeutic agents, diagnostic agents, and prophylactic agents. A fully human monoclonal antibody obtained by immunization using a transgenic mouse strain in which mouse antibody gene expression is suppressed and replaced with human antibody gene expression. [Selection figure] None |