abstract |
A nucleic acid molecule for suppressing expression of a TGF-β1 gene, a composition containing the nucleic acid molecule, and use thereof. A single-stranded nucleic acid molecule that suppresses the expression of a TGF-β1 gene, comprising only a region X, a linker region Lx, and a region Xc, wherein the Lx includes at least one of a pyrrolidine skeleton and a piperidine skeleton A nucleic acid molecule having a structure, wherein at least one of X and Xc includes an expression suppressing sequence that suppresses expression of a TGF-β1 gene. [Selection] Figure 1 |