| abstract |
Benzodiazepine compounds that inhibit binding between acetylated histones and bromodomain-containing proteins, pharmaceutical compositions containing such compounds, and their use in therapy. A benzodiazepine compound represented by the following formula, and a salt thereof, a pharmaceutical composition containing such a compound, and a treatment thereof, particularly those in the treatment of diseases or pathological conditions such as rheumatoid arthritis to which a bromodomain inhibitor is indicated. Use of. [Selection figure] None |