| abstract |
A binding protein that specifically binds to CD154 (CD40L) protein, comprising an antibody, an antibody derivative, and an antibody fragment. A humanized Fab fragment comprising a heavy chain variable sequence consisting of a specific amino acid sequence and a light chain variable sequence consisting of another specific amino acid sequence. The CD154 binding protein is useful in diagnostic and therapeutic methods, for example, in the treatment and prevention of diseases including those involving undesirable immune responses mediated by CD154-CD40 interactions. [Selection] Figure 19 |