| abstract |
The present invention provides a method for producing a triazole antifungal drug, efinaconazole, having high chemical purity and stereochemical purity. Reaction of a compound of formula (II) with a salt of formula (III) in the presence of a strong organic base and a Li salt, conversion of efinaconazole of formula (I) to its salt, efinaconazole A process for the preparation of efinaconazole of formula (I) comprising the conversion of a salt of [Selection figure] None |