| abstract |
An object of the present invention is to provide a preventive and / or therapeutic agent for new dementia induced by amyloid β protein, which is considered to be the main cause of Alzheimer's disease, particularly Alzheimer's disease. The present invention provides a preventive and / or therapeutic agent for dementia, particularly Alzheimer's disease, induced by amyloid β protein containing a compound having a GIRK channel activation current inhibitory action as an active ingredient. Examples of the compound include tipepidine, cloperastine, or a pharmacologically acceptable salt thereof. [Selection] Figure 2 |