| abstract |
PROBLEM TO BE SOLVED: To provide a prolyl tripeptidyl peptidase (PTP) inhibitor excellent in safety and a detection method capable of easily detecting a PTP inhibitory effect in gingiva. A PTP inhibitor comprising, as an active ingredient, a protein comprising a specific amino acid sequence derived from Oryza sativa. In the amino acid sequence, a protein having an amino acid sequence in which one or several amino acids are deleted, substituted, inserted and / or added, and having an inhibitory activity against PTP, or 90% or more homology with the amino acid sequence A PTP inhibitor comprising an effective amino acid sequence and a protein having inhibitory activity against PTP. A method for detecting PTP inhibitory activity comprising a step of contacting PTP with a structure containing gelatin in a medium in the presence of a PTP inhibitor to detect PTP activity. [Selection] Figure 3 |