| abstract |
Disclosed is a DNA vaccine based on the B7-1-PE40KDEL exotoxin fusion gene and use thereof. An exotoxin fusion protein B7-1-PE40KDEL gene encoded by a specific sequence. A DNA vaccine comprises the gene, a recombinant expression vector, which includes pcDNA3.1 / Zeo (+), pWLNEO, pSV2CAT, pOG44, pXT1, pSG, pSVK3, pBPV, pMSG, pSVL, and adenovirus. An exotoxin fusion gene B7-1-PE40KDEL operatively linked to a selected eukaryotic expression vector. [Selection figure] None |