abstract |
The present invention provides therapeutic compositions and / or formulations and methods of making them. The composition and / or formulation includes at least one cross-linked protein matrix and includes at least one protein residue and at least one residue having a sugar. The cross-linked protein matrix can be obtained by cross-linking a full-length or substantially full-length protein with a cross-linking agent having a sugar, such as tropoelastin, elastin, albumin, collagen, collagen. Monomers, immunoglobulins, insulin and / or derivatives or combinations thereof, polysaccharide cross-linking agents are derived from, for example, hyaluronic acid or cellulose derivatives. The composition can be administered topically or by infusion. Also methods, systems and / or kits for the preparation and / or preparation of compositions. [Selection] Figure 1 |